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Apremilast.svg Skeletal formula of apremilast Created using acdlabs html ACD Inkscape and vim Own work after cite journal Man HW Schafer Wong LM et al Discovery of ethoxymethoxyphenyl methanesulfonylethyl dioxo dihydroHisoindolyl acetamide apremilast potent and orally active phosphodiesterase and tumor necrosis factoralpha inhibitor