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Reaction of DHO to orotate.svg step of pyrimidine de novo synthesis oxidation of dehydroorotate to orotate by dehydroorotate dehydrogenase Schritt der PyrimidinDeNovoSynthese Oxidation von Dehydroorotat zu Orotat durch DehydroorotatDehydrogenase own Ilgom talk Chemical reactions Orotic acid